Participant nº

Participant legal name

Country

Organisation type

Name of scientific person in charge; role in the consortium

1a (coordinator)

Institut National de la Santé et de la Recherche Médicale (Inserm)

France

Research organisation

Raymond J. Pierce; coordinator, in vitro and in vivo testing of candidate drugs against schistosomes

1b

Jamal Khalife; in vitro and in vivo testing of candidate drugs against malaria parasites and schistosomes

2

Centre Européen de Recherche en Biologie et Medicine (CERBM)

France

Research organisation

Christophe Romier; production of recombinant enzymes, X-ray crystallography

3

Martin Luther Universität Halle- Wittenberg (MLU)

Germany

University

Wolfgang Sippl; in silico screening, protein structure modelling, chemical synthesis.

4

Universidade Federal do Rio de Janeiro (UFRJ)

Brazil

University

Marcello Fantappie; cDNA cloning, functional testing of enzymes and inhibitors

5

Universidade do Sao Paolo (USP)

Brazil

University

Sergio Verjovski-Almeida; transcriptomics of drug treated, or genetically manipulated parasites

6

Albert Ludwigs Universität Freiburg (ALU-FR)

Germany

University

Manfred Jung; assay development, compound testing, chemical synthesis

7a

Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz (Fiocruz)

Brazil

 

Research Organisation

 

Marina Mourão, Guilherme Oliveira; bioinformatics, Fiocruz Trypanosoma cruzi drug testing platform. In vitro and in vivo testing of candidate drugs against schistosomes.

7b

Instituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz)

Samuel Goldenberg; target validation, cDNA cloning, recombinant protein production, in vitro compound testing (T cruzi)

8

Inserm Transfert SA (IT)

France

Company

Delphine Smagghe; project management, intellectual property management, dissemination, exploitation of foreground.

9

Kancera AB

Sweden

SME

Johan Schultz; assay development, high-throughput screening, chemical synthesis, in-vitro ADMET

10

Adlego Biomedical AB (Adlego)

Sweden

SME

Urban Höglund; in vivo and in vitro pharmacology and toxicology testing. In vivo testing of compounds

11

Griffith University, Queensland Institute for Medical Research (GU)

Australia

University

Katherine Andrews; testing of candidate compounds against malaria parasites and enzymes, chemical synthesis

12

Universityof Queensland (UQ)

Australia

University

David Fairlie; chemical synthesis, pharmacology, drug development

13

Università degli Studi di Roma La Sapienza (UNIROMA1)

Italy

University

Antonello Mai; chemical synthesis

14        

University of East Anglia (UEA)

UK

University

A. Ganesan; chemical synthesis, compound development

15

Universidade Federal de Viçosa (UFV)

Brazil

University

Juliana Fietto; target validation, cDNA cloning, in vitro compound testing (Leishmania sp., T cruzi)

16 Institut Pasteur de Paris (IPP)  France Research Organisation Gérald Späth; target validation, in vitro inhibitor screening Leishmania sp